The Equine Pregnancy Laboratory conducts research to uncover the intricate processes involved in a successful pregnancy as well as how they go wrong in pregnancy loss and pregnancy pathologies. These processes play a crucial role not only in delivering a live foal but also in programming the fetus for lifelong health. By employing a multidisciplinary approach spanning genetics, molecular and cellular biology, pathology and epidemiology, we investigate critical aspects of early placental and fetal development in health and disease as well as congenital conditions of foals. Our long term goal is to improve fertility management and enhance the well-being of breeding mares through evidence-based clinical decisions. Furthermore, our discoveries may provide insights into pregnancy-related conditions in humans and other veterinary species due to the remarkable similarities we are discovering between pregnancy loss in mares and women.